Disable your installed antivirus programįix 1: Check If System Protection Is Disabled.Solutions to “Turn on System protection Greyed Out” So, based on these reasons, we would suggest you try the following solutions: Why does the issue happen? There are two main reasons: one is the interference from the installed antivirus program on your computer, and the other one is that the System protection feature has been disabled by the system administrator. So, I manually opened System Protection and found the setting 'Disable System Protection', and Windows10 would not allow me to manually Enable System Protection. Hundreds of Windows 10 users reported that they can’t turn on System Protection: Windows10 System Protection Cannot Be Turned On: I was trying to remove a file using Norton360 and it tried to set a System Restore Point, but Windows10 would not allow Norton360 to set a system restore point. Windows 10 Turn on System Protection Greyed Out